{"artifact_id":"L1-532","layer":"L1","title":"Confocal Fluorescence (pinhole-rejection livecell imaging)","domain":"Microscopy","sub_domain":"Laser-scanning confocal","physics_fingerprint":{"L_DAG":2.3,"title":"Confocal Fluorescence (pinhole-rejection livecell imaging)","domain":"Microscopy","carrier":"photon","primitives":["K.psf.confocal","S.scan.raster","int.temporal"],"sub_domain":"Laser-scanning confocal","noise_model":"poisson_gaussian","problem_class":"linear_inverse","solution_space":"2D_intensity","difficulty_delta":3,"integration_axis":"temporal","sensing_mechanism":"confocal_laser_scan"},"observable_profile":{"metric":"PSNR_dB","regime":"Existence of the recovered 2D intensity is guaranteed within the declared Omega bounds. Uniqueness holds on the measurement-supported subspace; out-of-support modes are controlled by the declared priors. Stability is well-conditioned (kappa_eff ~= 6); pinhole_size_AU dominates the stability cliff; scan_jitter and the remaining mismatch parameters contribute higher-order bias terms. Poisson signal noise + gaussian read noise sets the irreducible data-fidelity floor, while mild Tikhonov or analytic inversion is sufficient at the nominal Omega point.","secondary":"SSIM"},"size_tiers":{"center_spec":{"omega":{"H":1024,"W":1024,"NA":1.3,"pixel_nm":100,"pinhole_AU":1.0,"scan_jitter":0.0,"peak_photons":300,"photobleaching_rate":0.0},"input_format":"measurement_only","problem_class":"confocal_livecell","forward_operator":"confocal_livecell_forward","epsilon_fn_center":"28.0"},"omega_bounds":{"H":[256,4096],"W":[256,4096],"NA":[0.8,1.45],"pixel_nm":[50,300],"pinhole_AU":[0.5,3.0],"scan_jitter":[0.0,2.0],"peak_photons":[20,2000],"photobleaching_rate":[0.0,0.3]},"epsilon_bounds":{"psnr_db":[12.0,42.0]},"allowed_problem_classes":["confocal_livecell"],"allowed_omega_dimensions":["H","W","pixel_nm","NA","pinhole_AU","peak_photons","scan_jitter","photobleaching_rate","pinhole_size_AU","scan_jitter","photobleaching_rate"],"allowed_forward_operators":["confocal_livecell_forward"]},"hardness_fn":{"type":"epsilon_fn","delta":3,"kappa":120,"metric":"PSNR_dB"},"initiator_dataset":[{"name":"primary","weight":1.0,"ipfs_cid":null,"license_hash":null}],"status":"testnet","staked_pwm":0.0,"chain_hash":"0xa09c5807fdad118211a5cff701a0e131df45ab2369dade4e0856547e3e766578","chain_tx_hash":"0x18bacbe054b0dc110757f361b033b9a8fd6ff10281d263b7dee23606e07e6e0b","chain_block":41555318}