{"artifact_id":"L1-051","layer":"L1","title":"Proton Therapy (proton-beam radiation dose imaging)","domain":"Medical Imaging","sub_domain":"Dose-deposition imaging for Bragg-peak therapy","physics_fingerprint":{"L_DAG":4.0,"title":"Proton Therapy (proton-beam radiation dose imaging)","domain":"Medical Imaging","carrier":"photon","primitives":["L.proton_accelerator","L.bragg_peak_energy_deposition","D.dose_meter","int.spatial"],"sub_domain":"Dose-deposition imaging for Bragg-peak therapy","noise_model":"shot_poisson","problem_class":"nonlinear_inverse","solution_space":"3D_dose_distribution","difficulty_delta":5,"integration_axis":"spatial","sensing_mechanism":"proton_therapy_dose"},"observable_profile":{"metric":"PSNR_dB","regime":"Existence of the recovered 3D dose distribution is guaranteed within the declared Omega bounds. Uniqueness is local rather than global (non-convex landscape); convergence depends on initialisation and priors. Stability is moderately conditioned (kappa_eff ~= 15); range_uncertainty dominates the stability cliff; organ_motion and the remaining mismatch parameters contribute higher-order bias terms. Photon-shot-noise-limited (poisson counting) sets the irreducible data-fidelity floor, while mild Tikhonov or analytic inversion is sufficient at the nominal Omega point.","secondary":"SSIM"},"size_tiers":{"center_spec":{"omega":{"H":256,"W":256,"Z":128,"SNR_dB":30,"N_beams":3,"organ_motion":0.0,"proton_energy_MeV":150,"range_uncertainty":0.01,"tissue_heterogeneity":0.05,"CT_hu_calibration_error":0.0},"input_format":"measurement_only","problem_class":"proton_therapy","forward_operator":"proton_therapy_forward","epsilon_fn_center":"27.0"},"omega_bounds":{"H":128,"W":128,"Z":[32,512],"SNR_dB":[10.0,40.0],"N_beams":[1,16],"organ_motion":[0.0,0.3],"proton_energy_MeV":[70,250],"range_uncertainty":[0.0,0.05],"tissue_heterogeneity":[0.0,0.3],"CT_hu_calibration_error":[0.0,0.1]},"epsilon_bounds":{"psnr_db":[5.0,45.0]},"allowed_problem_classes":["proton_therapy"],"allowed_omega_dimensions":["H","W","Z","N_beams","proton_energy_MeV","SNR_dB","range_uncertainty","organ_motion","tissue_heterogeneity","CT_hu_calibration_error","range_uncertainty","organ_motion","tissue_heterogeneity","CT_hu_calibration_error"],"allowed_forward_operators":["proton_therapy_forward"]},"hardness_fn":{"type":"epsilon_fn","delta":5,"kappa":300,"metric":"PSNR_dB"},"initiator_dataset":[{"name":"primary","weight":1.0,"ipfs_cid":null,"license_hash":null}],"status":"testnet","staked_pwm":0.0,"chain_hash":"0x90a75deafb0a2ddf854fb59b7604011ab4e09f02d0650a2ebc7854a2a65e5020","chain_tx_hash":"0x900ff579a09bed5d80545525bac5238b8bca3a498a8476966153d190cd62b60a","chain_block":41553372}