# ⚛  L1 Principle — Fundus Imaging (retinal photography)

**ID:** `L1-049` · **Status:** ⊙ Testnet (genesis catalog)

> **🌐 Domain:** Medical Imaging — *Non-mydriatic retinal colour imaging*
> **🎯 Problem class:** linear inverse · **🧮 Solution space:** 2D retinal image
> **📡 Carrier:** photon · **🌫 Noise:** gaussian
> **⚖ Difficulty (δ):** 1 · **⛓ Block:** 41552302

---

## 🧠 1. Introduction

**Fundus Imaging (retinal photography)** is a **linear inverse problem** whose unknown lives in **2D retinal image** space, within the **Non-mydriatic retinal colour imaging** sub-domain of **Medical Imaging**.

Measurements consist of photons collected by an optical detector via a **fundus imaging** sensing mechanism.

The forward operator applies, in order: L · fundus flash operator; K · psf · eye pupil operator; pixel-level spatial averaging on the detector.

Observations are corrupted by additive Gaussian noise. Existence of the recovered 2D retinal image is guaranteed within the declared Omega bounds. Uniqueness holds on the measurement-supported subspace; out-of-support modes are controlled by the declared priors. Stability is well-conditioned (kappa_eff ~= 6); cataract_opacity dominates the stability cliff; reflex_artifact and the remaining mismatch parameters contribute higher-order bias terms. Additive gaussian thermal/electronic noise sets the irreducible data-fidelity floor, while mild Tikhonov or analytic inversion is sufficient at the nominal Omega point.

## ⚙ 2. Forward Model

Physical chain: **x** → L · fundus flash → K · psf · eye pupil → Spatial integration → **y** (detector).

```
y = ∫_A dA `K.psf.eye_pupil` `L.fundus_flash` x + n,    n ~ 𝒩(0, σ²)
```

**Measurement DAG:**

| Primitive | What it does |
|---|---|
| `L.fundus_flash` | L · fundus flash operator |
| `K.psf.eye_pupil` | K · psf · eye pupil operator |
| `int.spatial` | Pixel-level spatial averaging on the detector |

## 🔬 3. Physics Fingerprint

| Property | Value |
|---|---|
| Domain | Medical Imaging |
| Sub domain | Non-mydriatic retinal colour imaging |
| Carrier | photon |
| Problem class | linear_inverse |
| Solution space | 2D_retinal_image |
| Noise model | gaussian |
| Integration axis | spatial |
| Difficulty delta | 1 |
| L dag | 2.2 |

## 📡 4. Measurement Model

Existence of the recovered 2D retinal image is guaranteed within the declared Omega bounds. Uniqueness holds on the measurement-supported subspace; out-of-support modes are controlled by the declared priors. Stability is well-conditioned (kappa_eff ~= 6); cataract_opacity dominates the stability cliff; reflex_artifact and the remaining mismatch parameters contribute higher-order bias terms. Additive gaussian thermal/electronic noise sets the irreducible data-fidelity floor, while mild Tikhonov or analytic inversion is sufficient at the nominal Omega point.

| Metric | Value |
|---|---|
| Metric | PSNR_dB |
| Secondary | SSIM |

## 📏 5. Operating Range (Ω)

**Center problem class:** `fundus` · **Forward operator:** `fundus_forward`

**Center point:**

| Parameter | Unit | Value |
|---|---|---|
| H | px | 3000 |
| W | px | 3000 |
| Snr db | dB | 35 |
| Fov deg | deg | 45 |
| Pupil mm | mm | 4 |
| Misalignment | — | 0 |
| Reflex artifact | — | 0 |
| Cataract opacity | — | 0 |

**Allowed bounds:**

| Parameter | Unit | Range |
|---|---|---|
| H | px | 1024 |
| W | px | 1024 |
| Snr db | dB | 15.0 – 45.0 |
| Fov deg | deg | 20 – 60 |
| Pupil mm | mm | 2.0 – 8.0 |
| Misalignment | — | 0.0 – 0.5 |
| Reflex artifact | — | 0.0 – 0.3 |
| Cataract opacity | — | 0.0 – 0.5 |
| Pupil size variation | — | 0.0 – 0.3 |

## 🎯 6. Tolerance (ε)

**Center tolerance:** 33.0

| Metric | Range |
|---|---|
| Psnr db | 5.0 – 45.0 |

## ⚖ 7. Hardness Function

Hardness scales as **`epsilon_fn`** on **PSNR_dB**, with κ = `120` and δ = `1`.

## 💾 8. Reference Dataset

- **primary** · weight 1.0 · IPFS _(not pinned yet)_

## 9. On-chain Registration

- **Chain hash:** `0xd597946e16961f52230d2a0d7591520ad2f46f457aec566a2fc9c3ad61d95463`
- **Chain tx hash:** `0x688799a15f479f828c91b5b039cf11aa5c9c9b5bf799447d7ada1c23a818d7f6`
- **Chain block:** `41552302`

---

## File Mapping

This bundle consists of: `L1-049.md`, `L1-049.json`.

| File | Role | How to regenerate |
|------|------|-------------------|
| `L1-049.md` | Source of truth — edit this | Human or LLM |
| `L1-049.json` | Structured metadata for the registry | LLM regenerates from the sections above |

**Prompt for your LLM after editing this Markdown:**

> Read the attached Markdown. Regenerate the sibling `.json` so every field matches.
> Preserve the schema documented in the rows above.
> Output each file in its own fenced code block tagged with the filename.
> Output only the JSON object.

_This Markdown was auto-synthesized from the catalog row for `L1-049`._
_Edit it, regenerate the JSON, and submit at [/submit](/submit) to claim the artifact._