{"artifact_id":"L1-006","layer":"L1","title":"Light Sheet Fluorescence Microscopy (LSFM / SPIM)","domain":"Microscopy","sub_domain":"Selective plane illumination 3D imaging","physics_fingerprint":{"L_DAG":3.2,"title":"Light Sheet Fluorescence Microscopy (LSFM / SPIM)","domain":"Microscopy","carrier":"photon","primitives":["L.illumination.sheet","K.psf.detection","S.scan.axial","int.temporal"],"sub_domain":"Selective plane illumination 3D imaging","noise_model":"poisson_gaussian","problem_class":"linear_inverse","solution_space":"3D_intensity","difficulty_delta":3,"integration_axis":"axial","sensing_mechanism":"light_sheet_illumination"},"observable_profile":{"metric":"PSNR_dB","regime":"Existence of the recovered 3D intensity is guaranteed within the declared Omega bounds. Uniqueness holds on the measurement-supported subspace; out-of-support modes are controlled by the declared priors. Stability is moderately conditioned (kappa_eff ~= 10); sheet_thickness_nm dominates the stability cliff; sheet_tilt and the remaining mismatch parameters contribute higher-order bias terms. Poisson signal noise + gaussian read noise sets the irreducible data-fidelity floor, while mild Tikhonov or analytic inversion is sufficient at the nominal Omega point.","secondary":"SSIM"},"size_tiers":{"center_spec":{"omega":{"H":2048,"W":2048,"Z":200,"NA_det":1.0,"sheet_nm":2000,"z_step_nm":500,"sheet_tilt":0.0,"peak_photons":500,"sample_induced_aberration":0.0},"input_format":"measurement_only","problem_class":"lsfm","forward_operator":"lsfm_forward","epsilon_fn_center":"29.0"},"omega_bounds":{"H":[512,4096],"W":[512,4096],"Z":[32,1024],"NA_det":[0.8,1.2],"sheet_nm":[500,5000],"z_step_nm":[200,2000],"sheet_tilt":[0.0,0.05],"peak_photons":[50,5000],"sample_induced_aberration":[0.0,0.3]},"epsilon_bounds":{"psnr_db":[12.0,42.0]},"allowed_problem_classes":["lsfm"],"allowed_omega_dimensions":["H","W","Z","sheet_nm","z_step_nm","NA_det","peak_photons","sheet_tilt","sample_induced_aberration","sheet_thickness_nm","sheet_tilt","sample_induced_aberration"],"allowed_forward_operators":["lsfm_forward"]},"hardness_fn":{"type":"epsilon_fn","delta":3,"kappa":200,"metric":"PSNR_dB"},"initiator_dataset":[{"name":"primary","weight":1.0,"ipfs_cid":null,"license_hash":null}],"status":"testnet","staked_pwm":0.0,"chain_hash":"0x4552e070d72334485b84438a43401a9f2900af150b67411a605d469039af1ed8","chain_tx_hash":"0xf9bccafe6d9127f4a84d783a9d930d7f838b507744c534769e550555ddd1ef65","chain_block":41554154}