{"artifact_id":"L1-002","layer":"L1","title":"Low-Dose Widefield Fluorescence (photon-starved Airy deconvolution)","domain":"Microscopy","sub_domain":"Photon-limited epifluorescence","physics_fingerprint":{"L_DAG":1.0,"title":"Low-Dose Widefield Fluorescence (photon-starved Airy deconvolution)","domain":"Microscopy","carrier":"photon","primitives":["K.psf.airy","int.temporal"],"sub_domain":"Photon-limited epifluorescence","noise_model":"poisson_gaussian","problem_class":"linear_inverse","solution_space":"2D_intensity","difficulty_delta":3,"integration_axis":"temporal","sensing_mechanism":"fluorescence_widefield"},"observable_profile":{"metric":"PSNR_dB","regime":"Existence of the recovered 2D intensity is guaranteed within the declared Omega bounds. Uniqueness holds on the measurement-supported subspace; out-of-support modes are controlled by the declared priors. Stability is well-conditioned (kappa_eff ~= 8); dz_nm dominates the stability cliff; sigma_bg and the remaining mismatch parameters contribute higher-order bias terms. Poisson signal noise + gaussian read noise sets the irreducible data-fidelity floor, while mild Tikhonov or analytic inversion is sufficient at the nominal Omega point.","secondary":"SSIM"},"size_tiers":{"center_spec":{"omega":{"H":512,"W":512,"NA":1.4,"dz_nm":0.0,"pixel_nm":65,"sigma_bg":0.0,"peak_photons":50},"input_format":"measurement_only","problem_class":"airy_psf_low_dose","forward_operator":"airy_psf_low_dose","epsilon_fn_center":"24.0"},"omega_bounds":{"H":[128,4096],"W":[128,4096],"NA":[0.4,1.49],"dz_nm":[0.0,1500.0],"pixel_nm":[30,200],"sigma_bg":[0.0,0.1],"peak_photons":[5,200]},"epsilon_bounds":{"psnr_db":[12.0,42.0]},"allowed_problem_classes":["airy_psf_low_dose"],"allowed_omega_dimensions":["H","W","pixel_nm","NA","peak_photons","dz_nm","sigma_bg","dz_nm","sigma_bg","shot_noise_variance"],"allowed_forward_operators":["airy_psf_low_dose"]},"hardness_fn":{"type":"epsilon_fn","delta":3,"kappa":160,"metric":"PSNR_dB"},"initiator_dataset":[{"name":"primary","weight":1.0,"ipfs_cid":null,"license_hash":null}],"status":"testnet","staked_pwm":0.0,"chain_hash":"0x1c2c8279a42465282fd5ead803d6357541d23506fbee53091a428728b2f8c79a","chain_tx_hash":"0x9cc700a9bcfb032addb8f17b4ea344e0893361cc4cfc7dae30cd2732c395199d","chain_block":41554153}